Nemo  2.4.1
Simulate forward-in-time genetic evolution in a spatially explicit, individual-based stochastic simulator
TTQuanti_diallelic_full_pleio Class Reference

TTQuanti_diallelic_full_pleio : pleiotropic di-allelic loci, max PD = 2. More...

#include <ttquanti.h>

+ Inheritance diagram for TTQuanti_diallelic_full_pleio:
+ Collaboration diagram for TTQuanti_diallelic_full_pleio:

Public Member Functions

 TTQuanti_diallelic_full_pleio ()
 
 TTQuanti_diallelic_full_pleio (const TTQuanti_diallelic_full_pleio &TT)
 
virtual ~TTQuanti_diallelic_full_pleio ()
 
virtual void init_sequence ()
 
virtual TTQuanti_diallelic_full_pleioclone ()
 
virtual void show_up ()
 
virtual double get_additive_genotype (const unsigned int trait) const
 
virtual double get_dominant_genotype (const unsigned int trait) const
 
virtual void copy_sequence_block (sex_t SEX, unsigned int strand, unsigned int from_locus, unsigned int to_locus, const TTQuanti *parent)
 
virtual void copy_sequence_1locus (sex_t SEX, unsigned int strand, unsigned int at, const TTQuanti *parent)
 
- Public Member Functions inherited from TTQuanti_diallelic
 TTQuanti_diallelic ()
 
 TTQuanti_diallelic (const TTQuanti &T)
 
virtual ~TTQuanti_diallelic ()
 
virtual bool get_allele_bit (unsigned int position, unsigned int allele) const
 
virtual void set_allele_bit (unsigned int position, unsigned int allele, bool value)
 
void inherit_free (const TTrait *mother, const TTrait *father)
 
virtual void reset ()
 
virtual void init ()
 
virtual void set_sequence (void **seq)
 
virtual void ** get_sequence () const
 
virtual unsigned int get_allele (int loc, int all) const
 
virtual double get_allele_value (int locus, int allele) const
 
virtual void set_allele_value (unsigned int locus, unsigned int allele, double value)
 
virtual TTQuanti_diallelicoperator= (const TTrait &T)
 
virtual bool operator== (const TTrait &T)
 
virtual bool operator!= (const TTrait &T)
 
virtual void store_data (BinaryStorageBuffer *saver)
 
virtual bool retrieve_data (BinaryStorageBuffer *reader)
 
virtual double get_full_genotype (unsigned int trait)
 
virtual void set_allele (int locus, int allele, double value)
 
virtual void mutate_add (unsigned int position, unsigned int allele, double value)
 
virtual void mutate_inplace (unsigned int position, unsigned int allele, double value)
 
- Public Member Functions inherited from TTQuanti
 TTQuanti ()
 
 TTQuanti (const TTQuanti &T)
 
virtual ~TTQuanti ()
 
virtual trait_t get_type () const
 
virtual void mutate ()
 
virtual void inherit (const TTrait *mother, const TTrait *father)
 
virtual void * set_trait (void *value)
 
virtual void set_value ()
 
virtual void * getValue () const
 
void set_proto (TProtoQuanti *proto)
 
TProtoQuantiget_proto ()
 
double get_phenotype (unsigned int trai)
 
void set_phenotype (unsigned int trait, double value)
 
void reset_phenotype_to_genotypic_value ()
 
- Public Member Functions inherited from TTrait
virtual ~TTrait ()
 
- Public Member Functions inherited from StorableComponent
virtual ~StorableComponent ()
 

Additional Inherited Members

- Protected Attributes inherited from TTQuanti_diallelic
unsigned char ** _sequence
 
- Protected Attributes inherited from TTQuanti
double * _phenotypes
 
double * _genotypic_values
 
TProtoQuanti_myProto
 

Detailed Description

TTQuanti_diallelic_full_pleio : pleiotropic di-allelic loci, max PD = 2.

Constructor & Destructor Documentation

◆ TTQuanti_diallelic_full_pleio() [1/2]

TTQuanti_diallelic_full_pleio::TTQuanti_diallelic_full_pleio ( )
inline
358 : TTQuanti_diallelic() {}
TTQuanti_diallelic()
Definition: ttquanti.h:284

Referenced by clone().

+ Here is the caller graph for this function:

◆ TTQuanti_diallelic_full_pleio() [2/2]

TTQuanti_diallelic_full_pleio::TTQuanti_diallelic_full_pleio ( const TTQuanti_diallelic_full_pleio TT)
inline
360 : TTQuanti_diallelic(TT) {}

◆ ~TTQuanti_diallelic_full_pleio()

virtual TTQuanti_diallelic_full_pleio::~TTQuanti_diallelic_full_pleio ( )
inlinevirtual
362 {}

Member Function Documentation

◆ clone()

virtual TTQuanti_diallelic_full_pleio* TTQuanti_diallelic_full_pleio::clone ( )
inlinevirtual

Implements TTrait.

366 {return new TTQuanti_diallelic_full_pleio(*this);}
TTQuanti_diallelic_full_pleio()
Definition: ttquanti.h:358

References TTQuanti_diallelic_full_pleio().

◆ copy_sequence_1locus()

void TTQuanti_diallelic_full_pleio::copy_sequence_1locus ( sex_t  SEX,
unsigned int  strand,
unsigned int  at,
const TTQuanti parent 
)
inlinevirtual

Implements TTQuanti.

4280 {
4281  const unsigned char *orig = (const unsigned char*)parent->get_sequence()[strand];
4282  unsigned char *seq = _sequence[SEX];
4283  unsigned int from_pos = at * _myProto->get_num_traits();
4284 
4285  memcpy(&seq[from_pos], &orig[from_pos], _myProto->get_locus_byte_size());
4286 }
size_t get_locus_byte_size()
Definition: ttquanti.h:428
unsigned int get_num_traits()
Definition: ttquanti.h:422
unsigned char ** _sequence
Definition: ttquanti.h:321
TProtoQuanti * _myProto
Definition: ttquanti.h:106
virtual void ** get_sequence() const =0
sequence accessor.

References TTQuanti::_myProto, TTQuanti_diallelic::_sequence, TProtoQuanti::get_locus_byte_size(), TProtoQuanti::get_num_traits(), and TTrait::get_sequence().

◆ copy_sequence_block()

void TTQuanti_diallelic_full_pleio::copy_sequence_block ( sex_t  SEX,
unsigned int  strand,
unsigned int  from_locus,
unsigned int  to_locus,
const TTQuanti parent 
)
inlinevirtual

Implements TTQuanti.

4264 {
4265  assert(to_locus >= from_locus);
4266 
4267  const unsigned char* orig = (const unsigned char*)parent->get_sequence()[strand];
4268  unsigned char* seq = _sequence[SEX];
4269  unsigned int from_pos = from_locus * _myProto->get_num_traits();
4270 
4271  size_t block_size = (to_locus - from_locus) * _myProto->get_locus_byte_size();
4272 
4273  memcpy(&seq[from_pos], &orig[from_pos], block_size);
4274 }

References TTQuanti::_myProto, TTQuanti_diallelic::_sequence, TProtoQuanti::get_locus_byte_size(), TProtoQuanti::get_num_traits(), and TTrait::get_sequence().

◆ get_additive_genotype()

double TTQuanti_diallelic_full_pleio::get_additive_genotype ( const unsigned int  trait) const
inlinevirtual

Implements TTQuanti.

4224 {
4225  double genotype = 0;
4226  unsigned int L = _myProto->get_num_locus(); //number of loci
4227  unsigned int pos = _myProto->get_locus_seq_pos(0, trait); //starting position, all loci contiguous on the map
4228 
4229  for(unsigned int j = 0; j < L; ++j) {
4230  genotype += _myProto->get_seq_diallele_value( pos, _sequence[0][pos] );
4231  genotype += _myProto->get_seq_diallele_value( pos, _sequence[1][pos] );
4232  pos += _myProto->get_num_traits(); // stride size on the genome (all loci affect each trait)
4233  }
4234 
4235  return genotype;
4236 }
double get_seq_diallele_value(unsigned int position, unsigned int allele)
Definition: ttquanti.h:437
unsigned int get_locus_seq_pos(unsigned int loc, unsigned int trait)
Definition: ttquanti.h:452
unsigned int get_num_locus()
Definition: ttquanti.h:423

References TTQuanti::_myProto, TTQuanti_diallelic::_sequence, TProtoQuanti::get_locus_seq_pos(), TProtoQuanti::get_num_locus(), TProtoQuanti::get_num_traits(), and TProtoQuanti::get_seq_diallele_value().

◆ get_dominant_genotype()

double TTQuanti_diallelic_full_pleio::get_dominant_genotype ( const unsigned int  trait) const
inlinevirtual

Implements TTQuanti.

4242 {
4243  double genotype = 0;
4244  unsigned int L = _myProto->get_num_locus(); //number of loci
4245  unsigned int pos = _myProto->get_locus_seq_pos(0, trait); //starting position,
4246 
4247 
4248  for(unsigned int j = 0; j < L; ++j) {
4250  _myProto->get_seq_diallele_value( pos, _sequence[0][pos] ),
4251  _myProto->get_seq_diallele_value( pos, _sequence[1][pos] ),
4252  j,
4253  trait);
4254  pos += _myProto->get_num_traits(); // stride size on the genome (all loci affect each trait)
4255  }
4256 
4257  return genotype;
4258 }
double get_genotype_with_dominance(const double a1, const double a2, const unsigned int locus, const unsigned int trait)
Definition: ttquanti.cc:2538

References TTQuanti::_myProto, TTQuanti_diallelic::_sequence, TProtoQuanti::get_genotype_with_dominance(), TProtoQuanti::get_locus_seq_pos(), TProtoQuanti::get_num_locus(), TProtoQuanti::get_num_traits(), and TProtoQuanti::get_seq_diallele_value().

◆ init_sequence()

void TTQuanti_diallelic_full_pleio::init_sequence ( )
inlinevirtual

Implements TTrait.

4291 {
4292  //options:
4293  //0: no variation, all alleles set to 0
4294  //1: max variation, randomly set alleles at each locus
4295  //2: no variation and initialize with opposite effect alleles at alternating loci.
4296 
4297  if (_myProto->get_doInitMutation() == 0){
4298 
4299  memset(_sequence[0], 0, _myProto->get_seq_length());
4300  memset(_sequence[1], 0, _myProto->get_seq_length());
4301 
4302  // option 1: random allele at each position
4303  } else if (_myProto->get_doInitMutation() == 1) {
4304 
4305  for(unsigned int i = 0; i < _myProto->get_seq_length(); ++i) {
4306 
4307  // randomly set the allelic values
4308  _sequence[0][ i ] = RAND::RandBool();
4309  _sequence[1][ i ] = RAND::RandBool();
4310 
4311  }
4312 
4313  } else {
4314  //option 2; polarized di-allelic values; even locus set to +a, odd locus set to -a
4315 
4316  for(unsigned int t = 0; t < _myProto->get_num_traits(); ++t) {
4317  for(unsigned int i = 0; i < _myProto->get_num_locus(t); i++) { // process trait-wise
4318  // even locus
4319  if (i % 2 == 0){
4320  _sequence[0][ _myProto->get_locus_seq_pos(i, t) ] = 0;
4321  _sequence[1][ _myProto->get_locus_seq_pos(i, t) ] = 0;
4322  }
4323  else { // odd locus
4324  _sequence[1][ _myProto->get_locus_seq_pos(i, t) ] = 1;
4325  _sequence[0][ _myProto->get_locus_seq_pos(i, t) ] = 1;
4326  }
4327  }
4328 
4329  }
4330  }
4331 }
static bool RandBool()
Returns a random boolean.
Definition: Uniform.h:164
unsigned int get_seq_length()
Definition: ttquanti.h:426
unsigned int get_doInitMutation()
Definition: ttquanti.h:448

References TTQuanti::_myProto, TTQuanti_diallelic::_sequence, TProtoQuanti::get_doInitMutation(), TProtoQuanti::get_locus_seq_pos(), TProtoQuanti::get_num_locus(), TProtoQuanti::get_num_traits(), TProtoQuanti::get_seq_length(), and RAND::RandBool().

◆ show_up()

void TTQuanti_diallelic_full_pleio::show_up ( )
virtual

Implements TTrait.

4336 {
4337  message("\
4338  Trait's type: QUANTI (diallelic, full pleiotropy)\n\
4339  traits: %i\n\
4340  loci: %i\n\
4341  seq length: %i\n",_myProto->get_num_traits(),_myProto->get_num_locus()
4342  ,_myProto->get_seq_length());
4343 
4344  for(unsigned int i = 0; i < _myProto->get_num_traits(); i++)
4345  message("phenotype %i: %f\n",i+1,_phenotypes[i]);
4346 
4347  message("_sequence:");
4348 
4349  for(unsigned int i = 0; i < _myProto->get_num_traits(); ++i) {
4350 
4351  message("\nt%i (%i loci):\n[0]: ",i+1, _myProto->get_num_locus(i));
4352 
4353  for(unsigned int j = 0; j < _myProto->get_num_locus(i); ++j) {
4354  message("%.3f,",(double)_sequence[0][ _myProto->get_locus_seq_pos(j, i) ]);
4355  }
4356 
4357  message("\n[1]: ");
4358 
4359  for(unsigned int j = 0; j < _myProto->get_num_locus(i); ++j) {
4360  message("%.3f,",(double)_sequence[1][ _myProto->get_locus_seq_pos(j, i) ]);
4361  }
4362  }
4363 
4364  message("\n");
4365 
4366 }
double * _phenotypes
Definition: ttquanti.h:104
void message(const char *message,...)
Definition: output.cc:39

References TTQuanti::_myProto, TTQuanti::_phenotypes, TTQuanti_diallelic::_sequence, TProtoQuanti::get_locus_seq_pos(), TProtoQuanti::get_num_locus(), TProtoQuanti::get_num_traits(), TProtoQuanti::get_seq_length(), and message().


The documentation for this class was generated from the following files:

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